Glycated haemoglobin (HbA 1c ) monitoring

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Silent haemoglobin variants and determination of HbA(1c) with the HPLC Bio-Rad Variant II.

AIMS To evaluate the determination of HbA(1c) with an automated high performance liquid chromatography (HPLC) method in patients with clinically silent haemoglobin variants. METHODS HbA(1c) values were determined with the ion exchange HPL Bio-Rad Variant II using the high resolution beta thalassaemia programme in patients with silent haemoglobin variants, namely: Hb Graz, Hb Sherwood Forest, ...

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Interpretation of hemoglobin A(1c) (HbA(1c)) values among diabetic patients: implications for quality specifications for HbA(1c).

BACKGROUND Few studies have examined patients' views, knowledge, and understanding of glycohemoglobin A(1c) (HbA(1c)) testing. We explored such issues in patients with type 1 diabetes and used their statements to estimate analytical quality specifications for HbA(1c) testing. METHODS We recruited 201 patients from a hospital outpatient clinic. A questionnaire was used to collect information o...

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Is HbA(1c) affected by glycemic instability?

OBJECTIVE HbA(1c) is a standard clinical assessment of glycemia and the basis of most data relating glycemic control to complications. It remains unclear, however, whether HbA(1c) is affected by glycemic variation and mean glycemia. RESEARCH DESIGN AND METHODS To test this question, we analyzed the statistical relationship between HbA(1c) levels and glycemic variability as measured by self-mo...

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Difficulties in interpreting HbA(1c) results.

Glycated hemoglobin (HbA(1c)) is a parameter broadly employed in the assessment of glycemic control in diabetes. The 2010 "Standards of medical care in diabetes", published by the American Diabetes Association (ADA), recommended performing the HbA(1c) test at least every 6 months in patients in whom disease is clinically stable, while subjects after modifications of therapy or in whom glycemic ...

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What's in a name? Standardisation of HbA(1c): a response.

W. Garry John, Gunnar Nordin and Mauro Panteghini* 1 Clinical Biochemistry, Norfolk and Norwich University Hospital, and School of Medicine, Health Policy and Practice, UEA, Norwich, NR4 7UY, UK 2 External Quality Assurance in Laboratory Medicine in Sweden, Uppsala, Sweden 3 Centre for Metrological Traceability in Laboratory Medicine (CIRME) and Department of Clinical Sciences ‘‘Luigi Sacco’’, ...

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ژورنال

عنوان ژورنال: BMJ

سال: 2006

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.38947.627847.ae